Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864239 | 0.89 | — | — | |
| SCHEMBL23864302 | 0.87 | BCHE (0.31) | LMNAAVPR2 | |
| SCHEMBL23864573 | 0.82 | — | — | |
| SCHEMBL23864447 | 0.81 | AKR1C3 (0.36) | HPGDHTTALDH1A1MAPTLMNA | |
| SCHEMBL23864683 | 0.79 | NR1H4 (0.35) | HPGDHTTALDH1A1KDM4EGAA | |
| SCHEMBL23864599 | 0.79 | HTT (0.36) | HPGDHTTALDH1A1MAPTLMNA | |
| SCHEMBL23864267 | 0.75 | TAS1R3 (0.41) | HPGDNPC1RAB9AHTTALDH1A1 | |
| SCHEMBL23864738 | 0.75 | HPGD (0.34) | HPGDHTTALDH1A1KDM4ELMNA | |
| SCHEMBL23864208 | 0.73 | HPGD (0.32) | HPGDALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL23864539 | 0.72 | HPGD (0.33) | HPGDHTTALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |