Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864743 | 0.83 | HTT (0.32) | HPGDLMNAALDH1A1CD274CYP1A2 | |
| SCHEMBL23864208 | 0.82 | HPGD (0.32) | HPGDLMNAAPEX1ALDH1A1PDCD1 | |
| SCHEMBL23864683 | 0.78 | NR1H4 (0.35) | HPGDALDH1A1PDCD1CD274KMT2A | |
| SCHEMBL23864738 | 0.76 | HPGD (0.34) | TSHRHPGDLMNAAPEX1ALDH1A1 | |
| SCHEMBL23864347 | 0.75 | ALDH1A1 (0.37) | TSHRHPGDLMNAALDH1A1KMT2A | |
| SCHEMBL23864257 | 0.71 | CYP2C9 (0.35) | HPGDLMNAAPEX1ALDH1A1KMT2A | |
| SCHEMBL23864637 | 0.71 | TXNRD1 (0.37) | HPGDLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL23864366 | 0.71 | MAPT (0.37) | HPGDALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL23864723 | 0.71 | MAPT (0.37) | HPGDLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL20653537 | 0.70 | ALDH1A1 (0.38) | ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |