Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12114208 | 0.80 | S1PR1 (0.37) | DAOCYP1A2PDE3BPDE3ASIGMAR1 | |
| SCHEMBL19789643 | 0.80 | PDE3B (0.47) | DAOAOC3CYP1A2PDE3BPDE3A | |
| SCHEMBL12834802 | 0.78 | FFAR4 (0.40) | DAOCYP1A2CYP2C19HSPA5 | |
| SCHEMBL25562870 | 0.76 | DAO (0.42) | ESRRGDAOCYP1A2CYP2C19 | |
| SCHEMBL23865129 | 0.75 | TAAR1 (0.53) | DAOAOC3TAAR1 | |
| SCHEMBL13863236 | 0.73 | HSPA5 (0.42) | DAOPTPN7DUSP3CYP1A2HSPA5 | |
| SCHEMBL23463560 | 0.73 | HSPA5 (0.44) | CYP1A2HSPA5SIGMAR1 | |
| SCHEMBL24075223 | 0.72 | DAO (0.49) | DAOAOC3TAAR1CYP1A2CYP2C19 | |
| SCHEMBL20468369 | 0.72 | AR (0.43) | DAOKCNH2AOC3TAAR1CYP1A2 | |
| SCHEMBL7456580 | 0.72 | KCNH2 (0.59) | ESRRGDAOKCNH2GPR84GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436451-B1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2021-09-29 | — | — | EP | disclosed |