Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | DAO | P14920 | 5/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075223 | 0.81 | DAO (0.49) | TAAR1MAOBDAOAOC3 | |
| SCHEMBL23865166 | 0.80 | LOXL2 (0.39) | TAAR1MAOBIDO1 | |
| SCHEMBL19430923 | 0.78 | IDO1 (0.44) | TAAR1MAOBDAOIDO1AOC3 | |
| SCHEMBL23865172 | 0.78 | PTPN7 (0.45) | MAOB | |
| SCHEMBL17654431 | 0.77 | KIF11 (0.47) | TAAR1MAOBDAOAOC3MIF | |
| SCHEMBL4550353 | 0.76 | LOXL2 (0.41) | TAAR1MAOBIDO1 | |
| SCHEMBL17654672 | 0.76 | GRIN2B (0.41) | TAAR1MAOBDAOIDO1AOC3 | |
| SCHEMBL23865007 | 0.75 | ESRRG (0.41) | TAAR1DAOAOC3 | |
| SCHEMBL22483294 | 0.75 | GRIN2B (0.43) | TAAR1MAOBDAOIDO1AOC3 | |
| SCHEMBL108337 | 0.74 | TAAR1 (0.67) | TAAR1MAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436451-B1 | SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2021-09-29 | — | — | EP | disclosed |