Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.61 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.61 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.61 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.61 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12611015 | 0.88 | CHRM1 (0.83) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28652152 | 0.87 | SLC1A2 (0.63) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28647148 | 0.84 | CHRM1 (0.68) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2491997 | 0.84 | CHRM1 (0.68) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL11466744 | 0.84 | GRIK1 (0.66) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL6917703 | 0.84 | GRIK1 (0.66) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5514956 | 0.84 | GRIK1 (0.66) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL3861908 | 0.84 | GRIK1 (0.66) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL8044187 | 0.84 | GRIK1 (0.66) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL9418997 | 0.83 | SLC1A3 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110955-B1 | BRAIN-SPECIFIC DRUG DELIVERY | UNIV FLORIDA (US) | 1995-08-23 | — | — | EP | claimed |
| US-4945180-A | Process for the preparation of E-2-propyl-2-pentenoic acid and physiologically compatible salts thereof | DESITIN ARZNEIMITTEL GMBH (DE) | 1990-07-31 | — | — | US | claimed |
| EP-0224283-A2 | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1987-06-03 | — | — | EP | claimed |
| EP-0222425-A2 | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1987-05-20 | — | — | EP | claimed |
| EP-0218300-A2 | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1987-04-15 | — | — | EP | claimed |
| EP-3335140-B1 | SYSTEMS, APPARATUS, AND METHODS FOR ANALYZING AND PREDICTING CELLULAR PATHWAYS | MASSACHUSETTS INST TECHNOLOGY (US) | 2025-02-19 | — | — | EP | disclosed |
| EP-4181781-A1 | BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD | Universitäts-Kinderspital beider Basel (CH) | 2023-05-24 | — | — | EP | disclosed |
| CN-113594465-B | Negative electrode binder and preparation method and application thereof | 苏州清陶新能源科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-113594465-A | Negative electrode binder and preparation method and application thereof | 苏州清陶新能源科技有限公司 | 2021-11-02 | — | — | CN | disclosed |
| US-9023818-B2 | Pharmaceutical agents containing carbohydrate moieties and methods of their preparation and use | GLYCON LLC (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140057869-A9 | Novel Pharmaceutical Agents Containing Carbohydrate Moieties And Methods Of Their Preparation And Use | IMI INTERNATIONAL MEDICAL INNOVATIONS, INC. | 2014-02-27 | — | — | US | disclosed |
| US-20110237544-A1 | Novel Pharmaceutical Agents Containing Carbohydrate Moieties And Methods Of Their Preparation And Use | CHRISTIAN SAMUEL T | 2011-09-29 | — | — | US | disclosed |
| EP-0222425-A2 | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1987-05-20 | — | — | EP | disclosed |
| EP-0218300-A2 | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1987-04-15 | — | — | EP | disclosed |
| US-4540564-A | DIHYDROPYRIDINE AND/OR PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0110955-A1 | BRAIN-SPECIFIC DRUG DELIVERY. | UNIV FLORIDA (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4443365-A | Method for determination of the valproic acid and reagents therein | DAINIPPON PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0043285-B1 | METHOD FOR DETERMINATION OF VALPROIC ACID AND REAGENTS THEREIN | Dainippon Pharmaceutical Co., Ltd. (JP) | 1984-01-04 | — | — | EP | disclosed |
| WO-1983003968-A1 | BRAIN-SPECIFIC DRUG DELIVERY | UNIVERSITY OF FLORIDA (US) | 1983-11-24 | — | — | WO | disclosed |
| EP-0043285-A1 | Method for determination of valproic acid and reagents therein | Dainippon Pharmaceutical Co., Ltd. (JP) | 1982-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237544-A1 | Novel Pharmaceutical Agents Containing Carbohydrate Moieties And Methods Of Their Preparation And Use | CSGALNACT1, DDOST, STT3B | CHRM1 968/4885AKR1A1 1672/4885CHRM3 870/4885 |
| US-20140057869-A9 | Novel Pharmaceutical Agents Containing Carbohydrate Moieties And Methods Of Their Preparation And Use | CSGALNACT1, DDOST, STT3B | CHRM1 968/4885AKR1A1 1672/4885CHRM3 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.