Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.39 |
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14441125 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ATAD2PDE4AADORA2AADORA2B | |
| SCHEMBL21579656 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ATAD2PDE4AADORA2AADORA2B | |
| SCHEMBL13202761 | 0.79 | ADORA2A (0.51) | ALDH1A1ATAD2PDE4AADORA2AADORA2B | |
| SCHEMBL21273219 | 0.79 | PARP1 (0.41) | ALDH1A1ATAD2PDE4AADORA2AADORA2B | |
| SCHEMBL5429613 | 0.75 | ADORA2A (0.41) | ALDH1A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL5429656 | 0.71 | MEN1 (0.51) | ALDH1A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL1992701 | 0.71 | HPRT1 (0.54) | ALDH1A1ADORA2AADORA1HPRT1PNP | |
| SCHEMBL13587316 | 0.69 | IP6K1 (0.45) | ALDH1A1ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4379222 | 0.68 | ALDH1A1 (0.50) | ALDH1A1ATAD2PDE4AADORA2AADORA2B | |
| SCHEMBL18520815 | 0.68 | ADORA2A (0.64) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11376272-B2 | Methods of modulating immune activity | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2022-07-05 | — | — | US | disclosed |
| US-20210299155-A1 | METHODS OF MODULATING IMMUNE ACTIVITY | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11376272-B2 | Methods of modulating immune activity | STING1, IRF3, CGAS | ALDH1A1 4487/4885ATAD2 1348/4885PDE4A 70/4885 |
| US-20210299155-A1 | METHODS OF MODULATING IMMUNE ACTIVITY | STING1, IRF3, CGAS | ALDH1A1 4549/4885ATAD2 1518/4885PDE4A 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.