SCHEMBL23867306

SCHEMBL23867306

c1ccc2c(c1)oc1c(N(c3ccc(-c4ccc5c6ccccc6c6ccccc6c5c4)cc3)c3cccc4c3sc3ccccc34)cccc12

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.34
ESR2 Q92731 2/20 0.34
PRKDC P78527 1/20 0.33
ESR1 P03372 1/20 0.31
PLA2G2A P14555 2/20 0.30
PLA2G4A P47712 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15964392 0.92 ALOX5 (0.34) ALOX5ESR2PRKDCESR1
SCHEMBL15964389 0.92 ALOX5 (0.34) ALOX5ESR2PRKDCESR1
SCHEMBL22255537 0.91 ALOX5 (0.33) ALOX5ESR2PRKDCPLA2G2APLA2G4A
SCHEMBL23867337 0.91 ALOX5 (0.33) ALOX5ESR2PRKDC
SCHEMBL16385325 0.90 PLA2G2A (0.34) ALOX5ESR2PRKDCESR1PLA2G2A
SCHEMBL23867379 0.90 PRKDC (0.36) ALOX5ESR2PRKDCPLA2G2APLA2G4A
SCHEMBL22255642 0.90 ALOX5 (0.32) ALOX5ESR2ESR1PLA2G2APLA2G4A
SCHEMBL23867360 0.89 ALOX5 (0.34) ALOX5ESR2PRKDCPLA2G2APLA2G4A
SCHEMBL23867319 0.89 POLB (0.34) ALOX5ESR2
SCHEMBL23867307 0.89 ALOX5 (0.34) ALOX5ESR2PRKDCESR1PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210305509-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-09-30 US disclosed