Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 11/20 | 0.53 |
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27248392 | 0.88 | HPGD (0.50) | HTR2AHTR2C | |
| SCHEMBL23867520 | 0.86 | TDP1 (0.48) | — | |
| SCHEMBL27429930 | 0.82 | L3MBTL1 (0.60) | SRC | |
| SCHEMBL27248311 | 0.80 | HPGD (0.58) | HTR2AHTR2C | |
| SCHEMBL17716933 | 0.80 | HTR2C (0.50) | HTR2AHTR2C | |
| SCHEMBL27429987 | 0.78 | MAPT (0.48) | SRCHTR2AHTR2C | |
| SCHEMBL27248325 | 0.77 | HPGD (0.54) | HTR2AHTR2C | |
| SCHEMBL27248309 | 0.77 | SRC (0.52) | SRCHTR2AHTR2C | |
| SCHEMBL27248322 | 0.77 | L3MBTL1 (0.52) | SRCHTR2AHTR2C | |
| SCHEMBL27429484 | 0.77 | BCL6 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195279-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-09-30 | — | — | WO | disclosed |