Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.43 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867520 | 0.92 | TDP1 (0.48) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL27248325 | 0.91 | HPGD (0.54) | MAPTHPGDL3MBTL1CYBBNOX5 | |
| SCHEMBL27248311 | 0.91 | HPGD (0.58) | MAPTHPGDL3MBTL1CYBBNOX5 | |
| SCHEMBL27429469 | 0.88 | HPGD (0.45) | MAPTHPGDL3MBTL1CYBBNOX5 | |
| SCHEMBL27429930 | 0.88 | L3MBTL1 (0.60) | MAPTHPGDL3MBTL1CYBBNOX5 | |
| SCHEMBL17716933 | 0.83 | HTR2C (0.50) | MAPTHPGDL3MBTL1CYBBNOX4 | |
| SCHEMBL27248392 | 0.83 | HPGD (0.50) | MAPTHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL27430717 | 0.82 | ADRA2A (0.43) | MAPTHPGDL3MBTL1CYBBNOX5 | |
| SCHEMBL27429487 | 0.82 | ADRA2A (0.43) | MAPTHPGDL3MBTL1CYBBNOX5 | |
| SCHEMBL27430718 | 0.82 | ADRA2A (0.43) | MAPTHPGDL3MBTL1CYBBNOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |