SCHEMBL23868641

SCHEMBL23868641

CC(=O)CC[C@@H]1[C@@]2(C)CCCC(C)(C)C2CC[C@@]1(C)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
CYP3A4 P08684 2/20 0.57
CYP2C9 P11712 2/20 0.57
TSHR P16473 2/20 0.57
CYP2C19 P33261 2/20 0.57
MEN1 O00255 1/20 0.57
MAPT P10636 1/20 0.57
KMT2A Q03164 1/20 0.57
TRPV1 Q8NER1 1/20 0.51
TRPA1 O75762 2/20 0.44
PTPN1 P18031 3/20 0.39
PTPN2 P17706 2/20 0.39
UGT2B7 P16662 2/20 0.37
IDO1 P14902 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
PIK3CB P42338 1/20 0.34
EPAS1 Q99814 2/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25666845 1.00 ALDH1A1 (0.57) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL13987815 1.00 ALDH1A1 (0.57) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL10524433 0.87 ALDH1A1 (0.54) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL4351885 0.87 ALDH1A1 (0.54) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL10524625 0.87 ALDH1A1 (0.54) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL15494524 0.87 ALDH1A1 (0.52) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL14356925 0.87 ALDH1A1 (0.52) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL12234283 0.87 ALDH1A1 (0.52) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL9880747 0.87 ALDH1A1 (0.52) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19
Acetic Acid SCHEMBL8957441 0.85 ALDH1A1 (0.54) ALDH1A1CYP3A4CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572352-B2 Method for producing sclareolide SYMRISE AG (DE) 2023-02-07 US disclosed
US-20210300885-A1 METHOD FOR PRODUCING SCLAREOLIDE SYMRISE AG (DE) 2021-09-30 US disclosed