SCHEMBL4351885

SCHEMBL4351885

C/C(=C\C(=O)O)CC[C@@H]1[C@@]2(C)CCCC(C)(C)[C@@H]2CC[C@@]1(C)O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
MEN1 O00255 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 1/20 0.54
CYP2C9 P11712 1/20 0.54
TSHR P16473 1/20 0.54
CYP2C19 P33261 1/20 0.54
TRPV1 Q8NER1 1/20 0.46
TRPA1 O75762 2/20 0.42
TAS2R31 P59538 1/20 0.39
UGT2B7 P16662 5/20 0.38
PTPN2 P17706 2/20 0.37
PTPN1 P18031 2/20 0.37
HPGD P15428 1/20 0.35
TTL Q8NG68 3/20 0.35
PNLIP P16233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10524433 1.00 ALDH1A1 (0.54) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL10524625 1.00 ALDH1A1 (0.54) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL23868641 0.87 ALDH1A1 (0.57) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL13987815 0.87 ALDH1A1 (0.57) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL25666845 0.87 ALDH1A1 (0.57) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL16816911 0.85 ALDH1A1 (0.60) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL18949251 0.85 ALDH1A1 (0.60) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL16984792 0.85 ALDH1A1 (0.60) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL16816912 0.85 ALDH1A1 (0.60) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL18216691 0.85 ALDH1A1 (0.60) ALDH1A1MEN1CYP3A4MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921417-B2 Method of treating dyslipidemia using naturally occurring diterpene COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-12-30 US disclosed
US-20090247626-A1 Method of Treating Dyslipidemia Using Naturally Occurring Diterpene COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247626-A1 Method of Treating Dyslipidemia Using Naturally Occurring Diterpene DHCR7, LSS, HMGCR ALDH1A1 3654/4885MEN1 3173/4885CYP3A4 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.