Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23869552 | 0.78 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL12726833 | 0.77 | — | — | |
| SCHEMBL24892590 | 0.75 | CYP2C9 (0.30) | — | |
| SCHEMBL21719466 | 0.73 | — | — | |
| SCHEMBL23137446 | 0.72 | GLA (0.31) | HCAR2HCAR3 | |
| SCHEMBL16939220 | 0.71 | DYRK1A (0.33) | — | |
| SCHEMBL23869521 | 0.68 | — | — | |
| SCHEMBL32683672 | 0.67 | L3MBTL1 (0.30) | — | |
| SCHEMBL13683176 | 0.65 | ALOX15 (0.32) | — | |
| SCHEMBL18373780 | 0.65 | KDM5B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300906-A1 | PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300906-A1 | PYRAZOLE DERIVATIVES AS H4 ANTAGONIST COMPOUNDS | HRH4, HRH3, HDAC3 | HCAR2 16/4885HCAR3 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.