SCHEMBL2386975

SCHEMBL2386975

COC(=O)c1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.59
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA12 O43570 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
TDP1 Q9NUW8 1/20 0.57
CA7 P43166 1/20 0.57
SETD7 Q8WTS6 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
TSHR P16473 1/20 0.54
PTPN1 P18031 1/20 0.53
MAPT P10636 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TP53 P04637 1/20 0.51
EGFR P00533 1/20 0.51
ERN1 O75460 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7623 0.94 CA1 (0.64) CA1CA2CA12CA9CA14
Methane SCHEMBL2658014 0.91 CA1 (0.61) CA1CA2CA12CA9CA14
SCHEMBL11254482 0.91 CA1 (0.61) CA1CA2CA12CA9CA14
Hydrochloric Acid SCHEMBL31520543 0.91 CA1 (0.61) CA1CA2CA12CA9CA14
Biphenyl Dimethyl Dicarboxylate SCHEMBL68521 0.89 CA1 (0.70) CA1CA2CA12CA9CA14
SCHEMBL19387238 0.89 CA1 (0.70) CA1CA2CA12CA9CA14
SCHEMBL5346214 0.88 MAPT (0.66) CA1CA2CA12CA9CA14
Biphenyl Dimethyl Dicarboxylate SCHEMBL2890577 0.87 CA1 (0.67) CA1CA2CA12CA9CA14
SCHEMBL22531885 0.87 PTPN1 (0.75) TSHRPTPN1MAPTALDH1A1TP53
SCHEMBL13912441 0.86 CA1 (0.53) SLC6A3CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708370-A ASNF-M/SiO2@CPs hybrid copolymer gel and preparation method thereof 盐城市友普环保科技有限公司 2025-03-28 CN claimed
WO-2025034569-A9 STING INHIBITORS AND METHODS OF USING THEREOF UNIVERSITY OF MASSACHUSETTS (US) 2025-05-22 WO disclosed
CN-119708370-A ASNF-M/SiO2@CPs hybrid copolymer gel and preparation method thereof 盐城市友普环保科技有限公司 2025-03-28 CN disclosed
WO-2025034569-A2 STING INHIBITORS AND METHODS OF USING THEREOF UNIVERSITY OF MASSACHUSETTS (US) 2025-02-13 WO disclosed
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (assignee) (JP) 2024-12-26 US disclosed
EP-3808747-B1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL (JP) 2024-12-18 EP disclosed
US-12077531-B2 Imidazopyridinone compound KISSEI PHARMACEUTICAL CO., LTD. (JP) 2024-09-03 US disclosed
EP-3377473-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2024-06-19 EP disclosed
CN-112689637-B Imidazopyridone compounds 橘生药品工业株式会社 2023-11-10 CN disclosed
CN-116143618-B Metal organic frame material for water-based zinc ion battery, ligand and application 吉林省卓材新研科技有限公司 2023-08-01 CN disclosed
US-20040266789-A1 Substituted amino carboxylic acids INSTITUTE FOR DIABETES DISCOVERY, L.L.C. 2004-12-30 US disclosed
US-20040242572-A1 New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-12-02 US disclosed
WO-2004099170-A2 PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) 2004-11-18 WO disclosed
WO-2004099171-A2 SUBSTITUTED AMINO CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) 2004-11-18 WO disclosed
EP-1394158-A1 Novel compounds and optical elements using the same FUJI PHOTO FILM CO., LTD. (JP) 2004-03-03 EP disclosed
US-5922763-A ANTICOAGULANT; CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1999-07-13 US disclosed
US-5736559-A CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS KARL THOMAE GMBH (DE) 1998-04-07 US disclosed
US-5597825-A AGGREGATION INHIBITORS DR. KARL THOMAE GMBH (DE) 1997-01-28 US disclosed
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-5068300-A BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242572-A1 New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture MCHR2, MCHR1, NPY1R SLC6A3 1179/4885CA1 4351/4885CA2 952/4885
US-12077531-B2 Imidazopyridinone compound EGLN3, DHPS, EGLN2 SLC6A3 3231/4885CA1 1534/4885CA2 963/4885
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND EGLN3, DHPS, EGLN2 SLC6A3 3231/4885CA1 1534/4885CA2 963/4885
US-20040266789-A1 Substituted amino carboxylic acids PTPRS, PPM1B, PTPRO SLC6A3 1063/4885CA1 2350/4885CA2 2728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.