SCHEMBL7623

SCHEMBL7623

COC(=O)c1ccc(Br)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.64
CA2 P00918 4/20 0.64
CA12 O43570 2/20 0.64
CA7 P43166 2/20 0.64
CA9 Q16790 2/20 0.64
CA14 Q9ULX7 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
TSHR P16473 1/20 0.60
MAPT P10636 4/20 0.57
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
LMNA P02545 2/20 0.55
MAPK1 P28482 2/20 0.55
RAB9A P51151 2/20 0.55
LOXL2 Q9Y4K0 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL2658014 0.98 CA1 (0.61) CA1CA2CA12CA7CA9
SCHEMBL11254482 0.98 CA1 (0.61) CA1CA2CA12CA7CA9
Hydrochloric Acid SCHEMBL31520543 0.98 CA1 (0.61) CA1CA2CA12CA7CA9
SCHEMBL5346214 0.94 MAPT (0.66) CA1CA2CA12CA7CA9
SCHEMBL2386975 0.94 SLC6A3 (0.59) CA1CA2CA12CA7CA9
SCHEMBL6132139 0.90 CA1 (0.62) CA1CA2CA12CA7CA9
SCHEMBL2350832 0.88 PTPN1 (0.63) CA1CA2CA12CA7CA9
SCHEMBL21838795 0.88 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL2352849 0.88 PTPN1 (0.63) CA1CA2CA12CA7CA9
SCHEMBL4408660 0.88 NOTUM (0.54) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3138 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120152517-A OLED device with high exciton utilization rate and preparation method thereof 南京邮电大学 2025-06-13 CN claimed
CN-119972144-A Method for preparing phenol or ether compound by photocatalysis 中国科学院化学研究所 2025-05-13 CN claimed
CN-119775579-A Nickel-based metal organic framework, aniline compound and preparation methods of nickel-based metal organic framework and aniline compound 中国科学技术大学 2025-04-08 CN claimed
CN-119657225-A Cu-POM catalyst and preparation method and application thereof 中国药科大学 2025-03-21 CN claimed
CN-119320332-A Triphenylamine-containing dicarboxyl self-assembled hole transport material, synthesis method and application of triphenylamine-containing dicarboxyl self-assembled hole transport material as photoelectric device 南京理工大学 2025-01-17 CN claimed
CN-118373787-A Deuterated N-acyl sulfonamide compound and preparation method and application thereof 苏州九鹭生物医药有限公司 2024-07-23 CN claimed
CN-118373847-A Spiro self-assembled single-molecule hole transport material and preparation method and application thereof 华北电力大学 2024-07-23 CN claimed
CN-118084732-A 5-HTT/HDAC targeted double-target inhibitor and preparation method and application thereof 杭州师范大学 2024-05-28 CN claimed
CN-114716464-B Red light material based on aza beta diketone boron difluoride central core, preparation method and application thereof, and organic electroluminescent device 安徽秀朗新材料科技有限公司 2024-04-30 CN claimed
CN-117594772-A Graphene microsphere-based electrode material and preparation method thereof 上海博超纳烯新能源科技有限公司 2024-02-23 CN claimed
US-7825201-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2010-11-02 US claimed
US-20090299019-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (JP) 2009-12-03 US claimed
CN-101591247-A The method of synthetic 4-(4-methoxycarbonyl phenyl) butyraldehyde SHANGHAI DESANO PHARMACEUTICAL (CN) 2009-12-02 CN claimed
US-6586599-B1 Formating carbon-carbon bonds between carbocyclic halogen and organosilicon compounds in the presence of coordination catalysts, nitrogen compounds and bases; efficiency; catalysis UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION 2003-07-01 US claimed
US-6369265-B1 HETEROCOUPLING REACTION, MIXING IN A LIQUID AN ARYL HALIDE, BONDING TO AROMATIC RINGS, GRIGNARD REACTION, METAL COMPOUND AND HETEROCYCLIC CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-04-09 US claimed
WO-2001066248-A2 C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) 2001-09-13 WO claimed
CN-1070193-C Process for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid SYNTEX INC (US) 2001-08-29 CN claimed
CN-1149293-A Process for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid SYNTEX INC (US) 1997-05-07 CN claimed
US-5412102-A Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid SYNTEX (U.S.A.) INC. (US) 1995-05-02 US claimed
EP-0081384-B1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC CARBOXYLATED COMPOUNDS Montedison S.p.A. (IT) 1986-04-02 EP claimed