SCHEMBL18567239

SCHEMBL18567239

CC(=O)Oc1c(C)cc(Cc2cc(C)c(OC(C)(C)C)c(C)c2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
PPARA Q07869 9/20 0.38
HMGB1 P09429 1/20 0.37
CXCL12 P48061 1/20 0.37
CFD P00746 1/20 0.36
PPARG P37231 7/20 0.36
PPARD Q03181 6/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
ELANE P08246 1/20 0.33
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24932992 0.83 HTT (0.41) HTTKDM4EHSD17B10TP53GAA
SCHEMBL21232280 0.82 PPARA (0.33) HTTKDM4EHSD17B10TP53GAA
SCHEMBL5034651 0.81 HMGB1 (0.51) HTTKDM4EHSD17B10TP53GAA
SCHEMBL12445342 0.81 ALDH1A1 (0.44) HTTKDM4EHSD17B10TP53GAA
SCHEMBL14274965 0.79 ALDH1A1 (0.44) KDM4EHSD17B10PPARAPPARGPPARD
SCHEMBL23870271 0.76 HTT (0.39) HTTKDM4EHSD17B10TP53GAA
SCHEMBL1979635 0.75 CYP4F2 (0.51) HTTKDM4EHSD17B10TP53GAA
SCHEMBL24202214 0.74 HTT (0.45) HTTKDM4EHSD17B10TP53GAA
SCHEMBL1974691 0.74 HTT (0.45) HTTKDM4EHSD17B10TP53GAA
SCHEMBL23680460 0.73 MAPT (0.35) MAPTPPARAPPARGPPARDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008079-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT DIC株式会社 2023-02-02 WO disclosed
EP-2633369-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KK (JP) 2019-08-14 EP disclosed
EP-2646877-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KK (JP) 2017-03-01 EP disclosed