Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 7/20 | 0.42 |
| ▸ | PREP | P48147 | 6/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019478 | 0.87 | FAP (0.41) | FAPPREPDPP4ACEXIAP | |
| SCHEMBL30558187 | 0.86 | FAP (0.42) | FAPPREPDPP4ACEXIAP | |
| SCHEMBL30558194 | 0.86 | FAP (0.40) | FAPPREPDPP4ACEXIAP | |
| SCHEMBL30558197 | 0.82 | PREP (0.38) | FAPPREPDPP4ACECALCRL | |
| SCHEMBL29308708 | 0.82 | PREP (0.37) | FAPPREPDPP4ACECALCRL | |
| SCHEMBL26391683 | 0.81 | PREP (0.59) | FAPPREPDPP4ACE | |
| SCHEMBL30951791 | 0.80 | CALCRL (0.42) | FAPPREPDPP4ACEXIAP | |
| SCHEMBL31564810 | 0.80 | FAP (0.44) | FAPPREPDPP4ACEXIAP | |
| SCHEMBL22019176 | 0.79 | APLNR (0.33) | FAPPREPDPP4CALCRLKMT2A | |
| SCHEMBL29565573 | 0.78 | ACE (0.42) | FAPPREPDPP4ACEXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191689-A2 | TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS | YUYU PHARMA, INC. (KR) | 2021-09-30 | — | — | WO | disclosed |