SCHEMBL2387149

SCHEMBL2387149

CC(C)(C)C(C)(C)c1cc2ccccc2s1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.47
CYP2A6 P11509 4/20 0.43
ADRB2 P07550 1/20 0.43
ASIC3 Q9UHC3 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
BCL2L1 Q07817 1/20 0.41
CA2 P00918 2/20 0.40
APP P05067 2/20 0.39
AGXT P21549 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820486 0.83 MGLL (0.50) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL2388169 0.81 CYP2A6 (0.42) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL354292 0.81 CYP2A6 (0.48) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL16009726 0.79 MGLL (0.52) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL28019294 0.78 MGLL (0.50) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL2387733 0.76 CYP2A6 (0.44) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL2388308 0.76 MGLL (0.44) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL12778749 0.76 MGLL (0.44) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL8543672 0.74 CYP2A6 (0.50) MGLLCYP2A6ADRB2ASIC3LOXL2
SCHEMBL5720315 0.74 CYP2A6 (0.45) MGLLCYP2A6ADRB2ASIC3LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9969943-B2 Use of magnetic nanoparticles for depletion of aromatic compounds in oil MAERSK OLIE OG GAS A/S (DK) 2018-05-15 US disclosed
US-20160272898-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL TOTAL E&P DANMARK A/S (DK) 2016-09-22 US disclosed
WO-2015044449-A1 USE OF MAGNETIC NANOPARTICLES FOR DEPLETION OF AROMATIC COMPOUNDS IN OIL MÆRSK OLIE OG GAS A/S (DK) 2015-04-02 WO disclosed
US-8021540-B2 Method of desulfurizing hydrocarbon oil JAPAN ENERGY CORPORATION (JP) 2011-09-20 US disclosed
US-20100227229-A1 SOLID ACID, METHOD FOR PREPARING THE SOLID ACID, AND METHOD FOR DESULFURIZING HYDROCARBON OIL USING THE SOILD ACID AS DESULFURIZING AGENT JAPAN ENERGY CORPORATION (JP) 2010-09-09 US disclosed
EP-2202204-A1 SOLID ACID, PROCESS FOR PRODUCING THE SOLID ACID, METHOD FOR DESULFURIZING HYDROCARBON OIL USING SOLID ACID AS DESULFURIZING AGENT Japan Energy Corporation (JP) 2010-06-30 EP disclosed
US-20100155303-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2010-06-24 US disclosed
US-20090000990-A1 Method of Desulfurizing Hydrocarbon Oil JAPAN ENERGY CORPORATION (JP) 2009-01-01 US disclosed
EP-1923451-A1 METHOD FOR DESULFURIZATION OF HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2008-05-21 EP disclosed
EP-1715025-A1 METHOD OF DESULFURIZING HYDROCARBON OIL JAPAN ENERGY CORPORATION (JP) 2006-10-25 EP disclosed