SCHEMBL28019294

SCHEMBL28019294

CC(O)(Br)c1cc2ccccc2s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.50
CYP2A6 P11509 4/20 0.46
BCL2L1 Q07817 1/20 0.44
APP P05067 2/20 0.42
ADRB2 P07550 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
ASIC3 Q9UHC3 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16009726 0.86 MGLL (0.52) MGLLCYP2A6BCL2L1APPADRB2
SCHEMBL8543672 0.81 CYP2A6 (0.50) MGLLCYP2A6BCL2L1APPADRB2
SCHEMBL820486 0.81 MGLL (0.50) MGLLCYP2A6BCL2L1APPADRB2
SCHEMBL354292 0.79 CYP2A6 (0.48) MGLLCYP2A6BCL2L1APPADRB2
SCHEMBL2387149 0.78 MGLL (0.47) MGLLCYP2A6BCL2L1APPADRB2
SCHEMBL2387733 0.74 CYP2A6 (0.44) MGLLCYP2A6BCL2L1APPADRB2
SCHEMBL12778749 0.74 MGLL (0.44) MGLLCYP2A6BCL2L1APPADRB2
SCHEMBL2388308 0.74 MGLL (0.44) MGLLCYP2A6BCL2L1ADRB2ASIC3
SCHEMBL21646058 0.74 BCL2L1 (0.51) MGLLCYP2A6BCL2L1HDAC3HDAC4
SCHEMBL6207718 0.74 BCL2L1 (0.51) MGLLCYP2A6BCL2L1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104692987-A Cheap and efficient synthesis method of halogenated alcohols and derivatives thereof UNIV BEIJING 2015-06-10 CN disclosed