SCHEMBL2387285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2387282	1.00	LMNA (0.44)	LMNAGAAALDH1A1POLBRECQL
	SCHEMBL1463116	0.78	TDP1 (0.42)	LMNAGAAKMT2ASMN1; SMN2
	SCHEMBL19390846	0.78	ALDH1A1 (0.39)	ALDH1A1POLBKMT2AMEN1MAPT
	SCHEMBL14830081	0.78	ALDH1A1 (0.39)	ALDH1A1POLBKMT2AMEN1MAPT
	SCHEMBL2387995	0.78	CYP19A1 (0.41)	CRBN
	SCHEMBL2387992	0.78	CYP19A1 (0.41)	CRBN
	SCHEMBL1464332	0.78	TDP1 (0.42)	LMNAGAAKMT2ASMN1; SMN2
	SCHEMBL1273854	0.77	ALDH1A1 (0.39)	GAAALDH1A1KMT2AMAPTKDM4E
	SCHEMBL3398180	0.77	ALDH1A1 (0.39)	GAAALDH1A1KMT2AMAPTKDM4E
	SCHEMBL21121198	0.76	LMNA (0.50)	LMNAGAAALDH1A1POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.