Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | P4HB | P07237 | 2/20 | 0.47 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.47 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26440811 | 0.88 | LMNA (0.43) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL13435245 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL8399731 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL14302585 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL13461633 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL7028051 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL16327524 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL230379 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL7028056 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR | |
| SCHEMBL1527155 | 0.85 | TSHR (0.54) | LMNATHRBSMN1; SMN2HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191830-A1 | METHODS AND REAGENTS FOR SYNTHESIZING NUCLEOSIDES AND ANALOGUES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2021-09-30 | — | — | WO | disclosed |