Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.54 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14128961 | 0.86 | NPC1 (0.53) | ESR1ESR2NPC1RAB9AGAA | |
| SCHEMBL27154670 | 0.84 | SCD (0.56) | ESR1ESR2NPC1RAB9AGRIA1 | |
| SCHEMBL16000720 | 0.82 | ESR1 (0.40) | ESR1ESR2NPC1RAB9AGAA | |
| SCHEMBL16000697 | 0.80 | ESR1 (0.43) | ESR1ESR2NPC1RAB9AGAA | |
| SCHEMBL27154645 | 0.80 | NPC1 (0.55) | ESR1ESR2NPC1RAB9AGAA | |
| SCHEMBL18230901 | 0.80 | ESR1 (0.45) | ESR1ESR2NPC1RAB9AGAA | |
| SCHEMBL23874010 | 0.79 | ESR1 (0.46) | ESR1ESR2NPC1RAB9AGAA | |
| SCHEMBL804992 | 0.78 | ESR2 (0.73) | ESR1ESR2NPC1RAB9AGAA | |
| SCHEMBL2178266 | 0.78 | NPC1 (0.88) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL29386825 | 0.78 | NPC1 (0.88) | NPC1RAB9AGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2024-02-27 | — | — | US | disclosed |
| US-20210301085-A1 | POLYMERS DERIVED FROM 2,2'-BISIMIDAZOLES | UNITED STATES DEPARTMENT OF ENERGY | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210301085-A1 | POLYMERS DERIVED FROM 2,2'-BISIMIDAZOLES | PARG, PARN, NOP2 | ESR1 2764/4885ESR2 2825/4885NPC1 4196/4885 |
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | PARG, PARN, NOP2 | ESR1 2792/4885ESR2 2910/4885NPC1 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.