Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Robenidine SCHEMBL571509 | 0.91 | SMN1; SMN2 (0.53) | MAPTALDH1A1KDM4EAGTR1L3MBTL1 | |
| Robenidine SCHEMBL6729906 | 0.91 | SMN1; SMN2 (0.53) | MAPTALDH1A1KDM4EAGTR1L3MBTL1 | |
| Robenidine SCHEMBL3851893 | 0.90 | SMN1; SMN2 (0.51) | MAPTALDH1A1KDM4EAGTR1L3MBTL1 | |
| Robenidine SCHEMBL11769699 | 0.90 | SMN1; SMN2 (0.51) | MAPTALDH1A1KDM4EAGTR1L3MBTL1 | |
| SCHEMBL19449644 | 0.87 | LMNA (0.58) | MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17560983 | 0.85 | LMNA (0.56) | MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL16224325 | 0.83 | SMN1; SMN2 (0.54) | MAPTALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11233329 | 0.83 | MEN1 (0.57) | MAPTALDH1A1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11233334 | 0.83 | MEN1 (0.57) | MAPTALDH1A1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL23137364 | 0.83 | ESRRG (0.51) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191417-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF SYNUCLEINOPATHIES | SOM INNOVATION BIOTECH, S.A. (ES) | 2021-09-30 | — | — | WO | disclosed |