Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21577698 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL3437018 | 0.80 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL6997610 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL22273305 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL23815948 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL27872556 | 0.72 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ACA2LMNA | |
| SCHEMBL24242893 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL12243151 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL16002975 | 0.72 | ALDH1A1 (0.55) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL26899838 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ACA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300948-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300948-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | MCL1, PROX1, MKI67 | ALDH1A1 65/4885MEN1 3908/4885KMT2A 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.