Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.78 |
| ▸ | RCE1 | Q9Y256 | 7/20 | 0.77 |
| ▸ | P4HB | P07237 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | GRK6 | P43250 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21842444 | 0.90 | P4HB (0.77) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL5090192 | 0.90 | TP53 (1.00) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL21842443 | 0.89 | P4HB (0.74) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL23875094 | 0.89 | P4HB (0.74) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL29962903 | 0.87 | RCE1 (1.00) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL23359134 | 0.87 | RCE1 (1.00) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL31741895 | 0.87 | RCE1 (1.00) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL31741894 | 0.87 | RCE1 (1.00) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL23854803 | 0.85 | TP53 (0.82) | TP53CYP2C9CYP2C19HIF1AHSD17B10 | |
| SCHEMBL13836221 | 0.85 | P4HB (1.00) | TP53CYP2C9CYP2C19HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210299070-A1 | METHODS OF TREATING CREATINE TRANSPORTER DEFICIENCY | JNANA THERAPEUTICS INC. | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299070-A1 | METHODS OF TREATING CREATINE TRANSPORTER DEFICIENCY | SLC19A1, SLC1A5, SLC1A2 | TP53 4180/4885CYP2C9 3278/4885CYP2C19 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.