Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23875628 | 0.83 | ALDH1A1 (0.44) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL23875666 | 0.82 | EGLN3 (0.44) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL30059669 | 0.82 | EGLN3 (0.44) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL23875457 | 0.75 | ALDH1A1 (0.48) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL25783395 | 0.68 | CYP24A1 (0.46) | SMN1; SMN2KDM4EMEN1KMT2ACYP19A1 | |
| SCHEMBL23875533 | 0.67 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL25783758 | 0.66 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL25783423 | 0.66 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL23875449 | 0.65 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 | |
| SCHEMBL25785696 | 0.65 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |