Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23875628 | 0.90 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL25792508 | 0.79 | EGLN3 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL23875889 | 0.75 | MAPT (0.34) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL23875449 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL25785696 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL25783758 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL23875533 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL25783423 | 0.71 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL3461721 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL23875539 | 0.70 | HTR1B (0.48) | KDM4ELMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | ALDH1A1 133/4885KDM4E 1282/4885SMN1; SMN2 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.