Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8776347 | 0.82 | — | — | |
| SCHEMBL8718649 | 0.80 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7913217 | 0.79 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4120454 | 0.78 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7913244 | 0.78 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL613622 | 0.78 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9278341 | 0.77 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9278267 | 0.76 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3687437 | 0.76 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8142260 | 0.76 | MEN1 (0.35) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464684-B1 | Syndiotactic crystalline copolymers of propylene | SPHERILENE SRL (IT) | 1995-06-14 | — | — | EP | claimed |
| EP-0422703-B1 | CATALYST AND PROCESS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS | Enichem Anic S.r.l. (IT) | 1993-06-30 | — | — | EP | claimed |
| EP-0422703-A1 | Catalyst and process for the polymerization and copolymerization of alpha-olefins | Enichem Anic S.r.l. (IT) | 1991-04-17 | — | — | EP | claimed |
| JP-3217442-A | — | — | None | — | — | JP | disclosed |
| JP-3012439-A | — | — | None | — | — | JP | disclosed |
| JP-4001210-A | — | — | None | — | — | JP | disclosed |
| JP-2269705-A | — | — | None | — | — | JP | disclosed |
| JP-2292311-A | — | — | None | — | — | JP | disclosed |
| JP-3139506-A | — | — | None | — | — | JP | disclosed |
| JP-3070713-A | — | — | None | — | — | JP | disclosed |
| US-8017705-B2 | Process for production of syndiotactic propylene polymer | MITSUI CHEMICALS, INC. (JP) | 2011-09-13 | — | — | US | disclosed |
| EP-0428972-A2 | Moulded articles of syndiotactic polypropylene and method for preparing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0422498-A2 | Butene-1 copolymers | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-04-17 | — | — | EP | disclosed |
| EP-0419677-A1 | SYNDIOTACTIC POLYPROPYLENE RESIN COMPOSITION | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-04-03 | — | — | EP | disclosed |
| JP-H0370713-A | COPOLYMER OF PROPYLENE AND BUTENE | MITSUI TOATSU CHEM INC | 1991-03-26 | — | — | JP | disclosed |
| EP-0414202-A2 | Novel extruded polypropylene films and sheets | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |
| JP-H0312439-A | SYNDIOTACTIC POLYPROPYLENE RESIN COMPOSITION AND PRODUCTION THEREOF | MITSUI TOATSU CHEM INC | 1991-01-21 | — | — | JP | disclosed |
| EP-0403866-A1 | Novel Poly-alfa-olefins | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-12-27 | — | — | EP | disclosed |
| JP-H02292311-A | PRODUCTION OF SYNDIOTACTIC POLYPROPYLENE | MITSUI TOATSU CHEM INC | 1990-12-03 | — | — | JP | disclosed |
| JP-H02269705-A | POLYMERIZATION OF ETHYLENE | MITSUI TOATSU CHEM INC | 1990-11-05 | — | — | JP | disclosed |