Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4120454 | 0.83 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| Methane SCHEMBL8679931 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8710753 | 0.81 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7625234 | 0.81 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6437443 | 0.81 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8853881 | 0.81 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8679490 | 0.81 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5688623 | 0.80 | — | — | |
| SCHEMBL8718649 | 0.80 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8733761 | 0.79 | POLB (0.30) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255425-B1 | EXTRUDED ARTICLE FORMED BY EXTRUSION OF SYNDIOTACTIC PROPYLENE HOMOPOLYMER HAVING SYNDIOTACTIC PENTAD FRACTION OF AT LEAST 0.7 | MITSUI CHEMICALS, INC. (JP) | 2001-07-03 | — | — | US | claimed |
| CN-1031580-C | Catalyst and process for polymerization and copolymerization of alpha-olefins | ENICHEM ANIC SPA (IT) | 1996-04-17 | — | — | CN | claimed |
| EP-0464684-B1 | Syndiotactic crystalline copolymers of propylene | SPHERILENE SRL (IT) | 1995-06-14 | — | — | EP | claimed |
| EP-0464684-A2 | Syndiotactic crystalline copolymers of propylene | SPHERILENE S.r.l. (IT) | 1992-01-08 | — | — | EP | claimed |
| CN-1051363-A | The catalyzer of alpha-olefine polymerizing and copolymerization and method | ENICHEM ANIC SPA (IT) | 1991-05-15 | — | — | CN | claimed |
| JP-5156033-A | — | — | None | — | — | JP | disclosed |
| JP-6087930-A | — | — | None | — | — | JP | disclosed |
| CN-101528784-B | Process for producing syndiotactic propylene polymer | MITSU CHEMICALS INC | 2012-09-05 | — | — | CN | disclosed |
| CN-101528784-A | Process for producing syndiotactic propylene polymer | MITSUI CHEMICALS INC (JP) | 2009-09-09 | — | — | CN | disclosed |
| CN-100369967-C | Syndiotactic propylene polymer composition | MITSUI CHEMICALS INC (JP) | 2008-02-20 | — | — | CN | disclosed |
| CN-1751090-A | Syndiotactic propylene polymer composition | MITSUI CHEMICALS INC (JP) | 2006-03-22 | — | — | CN | disclosed |
| US-6255425-B1 | EXTRUDED ARTICLE FORMED BY EXTRUSION OF SYNDIOTACTIC PROPYLENE HOMOPOLYMER HAVING SYNDIOTACTIC PENTAD FRACTION OF AT LEAST 0.7 | MITSUI CHEMICALS, INC. (JP) | 2001-07-03 | — | — | US | disclosed |
| US-5759469-A | WITH EXCELLENT TRANSPARENCY THROUGH HEATING, MELTING AND HOT MOLDING | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-02 | — | — | US | disclosed |
| CN-1033956-C | Molded articles of syndiotactic polypropylene and method for preparing same | MITSUI TOATSU CHEMICALS (JP) | 1997-02-05 | — | — | CN | disclosed |
| EP-0464684-B1 | Syndiotactic crystalline copolymers of propylene | SPHERILENE SRL (IT) | 1995-06-14 | — | — | EP | disclosed |
| JP-H0687930-A | SYNDIOTACTIC CRYSTALLINE COPOLYMER OF PROPYLENE | HIMONT INC | 1994-03-29 | — | — | JP | disclosed |
| JP-H05156033-A | PR0DUCTION OF CROSSLINKED POLYOLEFIN MOLDING | MITSUI TOATSU CHEM INC | 1993-06-22 | — | — | JP | disclosed |
| EP-0464684-A2 | Syndiotactic crystalline copolymers of propylene | SPHERILENE S.r.l. (IT) | 1992-01-08 | — | — | EP | disclosed |
| CN-1057056-A | Novel poly-alpha olefins | MITSUI TOATSU CHEMICALS (JP) | 1991-12-18 | — | — | CN | disclosed |
| CN-1052077-A | Molded articles of syndiotactic polypropylene and manufacture method thereof | MITSUI TOATSU CHEMICALS (JP) | 1991-06-12 | — | — | CN | disclosed |