SCHEMBL23877612

SCHEMBL23877612

CC(C)S(=O)(=O)Nc1cc(C(F)(F)F)ccc1C(=O)NC12CC(c3ccccc3)(C1)C2

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC6A9 P48067 6/20 0.41
▸ USP2 O75604 6/20 0.39
▸ USP8 P40818 6/20 0.39
▸ ACLY P53396 5/20 0.39
▸ CXCR5 P32302 1/20 0.37
▸ KDM1A O60341 1/20 0.37
▸ USP36 Q9P275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23877557 0.87 ACLY (0.39) SLC6A9USP2USP8ACLYCXCR5
SCHEMBL23879533 0.86 ACLY (0.36) ACLY
SCHEMBL23877572 0.84 USP2 (0.49) USP2USP8ACLYKDM1AUSP36
SCHEMBL23141330 0.83 TNF (0.37) USP2USP8ACLYCXCR5KDM1A
SCHEMBL23141458 0.83 CNR2 (0.41) USP2USP8ACLYCXCR5KDM1A
SCHEMBL23877465 0.82 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL23877582 0.82 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL23877568 0.81 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL29460194 0.81 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL31046888 0.80 USP2 (0.47) USP2USP8ACLYKDM1AUSP36

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 — — US disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 — — US disclosed
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2024-07-30 — — US disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed
CN-112204008-A Sulphonylaminobenzylamide and sulphonylaminobenzamide derivatives 吉利德科学公司 2021-01-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B SLC6A9 489/4885USP2 3178/4885USP8 3142/4885
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B SLC6A9 489/4885USP2 3178/4885USP8 3142/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 SLC6A9 846/4885USP2 3926/4885USP8 3201/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B SLC6A9 489/4885USP2 3178/4885USP8 3142/4885
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B SLC6A9 489/4885USP2 3178/4885USP8 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback