SCHEMBL2387771

SCHEMBL2387771

CC(C)(C)c1cc(CCC(N)=O)cc(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.50
RXRB P28702 3/20 0.50
RXRG P48443 3/20 0.50
GAA P10253 2/20 0.42
TP53 P04637 1/20 0.42
RAB9A P51151 1/20 0.42
KLF5 Q13887 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CAPN1 P07384 1/20 0.42
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.38
HTR1D P28221 2/20 0.38
HTR1B P28222 1/20 0.38
ELANE P08246 1/20 0.37
CD69 Q07108 1/20 0.37
KMT2A Q03164 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14672764 0.91 RXRA (0.45) RXRARXRBRXRGGAATP53
SCHEMBL27871629 0.84 RXRA (0.53) RXRARXRBRXRGGAAGABRA1
SCHEMBL9702460 0.82 RXRA (0.70) RXRARXRBRXRGGABRA1GABRB2
SCHEMBL10751069 0.82 RXRA (0.51) RXRARXRBRXRGGAATP53
SCHEMBL12993402 0.82 CYP1A2 (0.45) RXRARXRBRXRGTP53RAB9A
SCHEMBL3400672 0.81 IDO1 (0.46) RXRARXRBRXRGGAACAPN1
Methane SCHEMBL9419508 0.81 RXRA (0.68) RXRARXRBRXRGELANECD69
SCHEMBL12993264 0.81 NR1H4 (0.53) RXRARXRBRXRGGAATP53
SCHEMBL7918647 0.78 RXRA (0.47) RXRARXRBRXRGGAASMN1; SMN2
SCHEMBL299811 0.78 GAA (0.69) GAATP53SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2366732-B1 Mixtures of sterically hindered amines for polymer stabilisation 3V SIGMA SPA (IT) 2013-06-26 EP disclosed
EP-2366732-A2 Mixtures of sterically hindered amines for polymer stabilisation 3V SIGMA S.p.A (IT) 2011-09-21 EP disclosed