Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.51 |
| ▸ | RXRB | P28702 | 6/20 | 0.51 |
| ▸ | RXRG | P48443 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753794 | 0.89 | RXRA (0.43) | RXRARXRBRXRGALDH1A1KDM4E | |
| SCHEMBL27871629 | 0.86 | RXRA (0.53) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL10750814 | 0.85 | LMNA (0.51) | RXRARXRBRXRGALDH1A1GABRA1 | |
| SCHEMBL9702460 | 0.84 | RXRA (0.70) | RXRARXRBRXRGGABRA1GABRB2 | |
| Methane SCHEMBL9419508 | 0.82 | RXRA (0.68) | RXRARXRBRXRGELANECD69 | |
| SCHEMBL13059753 | 0.82 | ALDH1A1 (0.47) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL2387771 | 0.82 | RXRA (0.50) | RXRARXRBRXRGALDH1A1GABRA1 | |
| SCHEMBL15032898 | 0.82 | ALDH1A1 (0.56) | RXRARXRBRXRGALDH1A1KDM4E | |
| SCHEMBL2953957 | 0.80 | ALDH1A1 (0.59) | RXRARXRBRXRGALDH1A1NPC1 | |
| SCHEMBL27999999 | 0.79 | RXRA (0.47) | RXRARXRBRXRGGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647579-A | Circulation active novel substituted 4-hydroxy-benzopyrans | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | disclosed |