Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190047 | 0.83 | TPMT (0.50) | LMNACA1CA2CA12CA4 | |
| SCHEMBL28993336 | 0.81 | CA12 (0.62) | LMNAALDH1A1CA1CA2CA12 | |
| SCHEMBL2803303 | 0.81 | LMNA (0.58) | LMNAALDH1A1KDM4ECA1CA2 | |
| SCHEMBL18624970 | 0.80 | TTR (0.46) | ALDH1A1KDM4ECA1CA2CA12 | |
| SCHEMBL27902481 | 0.77 | LMNA (0.61) | LMNAALDH1A1KDM4ECA1CA2 | |
| SCHEMBL2039734 | 0.76 | ALDH1A1 (0.63) | LMNAALDH1A1KDM4ECA1CA2 | |
| SCHEMBL29788029 | 0.76 | ALDH1A1 (0.63) | LMNAALDH1A1KDM4ECA1CA2 | |
| SCHEMBL1251597 | 0.75 | CA12 (0.62) | LMNAALDH1A1KDM4ECA1CA2 | |
| SCHEMBL5150983 | 0.74 | SMN1; SMN2 (0.66) | LMNAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL6248458 | 0.73 | LMNA (0.68) | LMNAALDH1A1KDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3387004-B1 | CYCLIC PEPTIDES TARGETING ALPHA4 BETA7 INTEGRIN | ZEALAND PHARMA AS (DK) | 2021-10-06 | — | — | EP | claimed |