Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17825333 | 0.87 | ALDH1A1 (0.63) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18824341 | 0.86 | ALDH1A1 (0.62) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL22050819 | 0.85 | STS (0.62) | ALDH1A1MMP1MMP2MMP9MMP8 | |
| SCHEMBL30498701 | 0.82 | ALDH1A1 (0.56) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20744267 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPT | |
| SCHEMBL23348324 | 0.81 | STS (0.57) | ALDH1A1MMP1MMP2MMP9MMP8 | |
| SCHEMBL25339246 | 0.81 | ALDH1A1 (0.57) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29134140 | 0.81 | ALDH1A1 (0.55) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL21815402 | 0.79 | ALDH1A1 (0.57) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20401085 | 0.78 | ALDH1A1 (0.76) | ALDH1A1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888651-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | Kyushu University, National University Corporation (JP) | 2021-10-06 | — | — | EP | disclosed |