Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | ACLY | P53396 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | USP8 | P40818 | 4/20 | 0.43 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24268165 | 0.89 | KDM1A (0.51) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL23879629 | 0.88 | KDM1A (0.50) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL23879571 | 0.88 | KDM1A (0.50) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL23879578 | 0.88 | USP2 (0.46) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL23879530 | 0.88 | ACLY (0.52) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL24268128 | 0.87 | KDM1A (0.49) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL23879544 | 0.87 | KDM1A (0.49) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL24268146 | 0.85 | KDM1A (0.48) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL24268109 | 0.85 | KDM1A (0.48) | KDM1AACLYUSP2USP8USP36 | |
| SCHEMBL23879553 | 0.84 | KDM1A (0.45) | KDM1AACLYUSP2USP8USP36 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220055985-A1 | SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES | GILEAD SCIENCES, INC. | 2022-02-24 | — | — | US | disclosed |
| US-11136290-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | THE LIVER COMPANY INC. (US) | 2021-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220055985-A1 | SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES | STS, SULT2A1, SCN2B | KDM1A 2735/4885ACLY 2228/4885USP2 3178/4885 |
| US-11136290-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | STS, SULT2A1, SCN2B | KDM1A 2735/4885ACLY 2228/4885USP2 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.