⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480235 | 0.75 | — | — | |
| SCHEMBL15787947 | 0.73 | — | — | |
| SCHEMBL23432966 | 0.69 | — | — | |
| SCHEMBL91192 | 0.67 | — | — | |
| SCHEMBL21788095 | 0.67 | ADRB2 (0.36) | — | |
| SCHEMBL9407492 | 0.67 | ADRB2 (0.36) | — | |
| SCHEMBL24344281 | 0.67 | LMNA (0.32) | — | |
| SCHEMBL21788078 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL7781983 | 0.65 | — | — | |
| SCHEMBL18655521 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136320-B2 | Fused ring derivative used as FGFR4 inhibitor | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-10-05 | — | — | US | disclosed |