Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002714 | 0.82 | HSP90AB1 (0.41) | KDM4ELMNAMMP1MMP3MMP7 | |
| SCHEMBL25332706 | 0.79 | KDM4E (0.55) | KDM4ELMNAMMP1MMP3MMP7 | |
| SCHEMBL289813 | 0.76 | KDM4E (0.52) | KDM4ELMNAMMP1MMP3MMP7 | |
| SCHEMBL23879789 | 0.75 | MMP3 (0.56) | KDM4ELMNAMMP1MMP3MMP7 | |
| SCHEMBL6849922 | 0.75 | MAPT (0.53) | KDM4ECA9MAPTALDH1A1THRB | |
| SCHEMBL11386832 | 0.75 | HSP90AB1 (0.41) | KDM4ELMNACA9HSP90AB1MAPT | |
| SCHEMBL7752801 | 0.75 | KMT2A (0.39) | KDM4ECA9HSP90AB1MAPTALDH1A1 | |
| SCHEMBL13947098 | 0.75 | KDM4E (0.50) | KDM4ELMNAMMP1MMP3MMP7 | |
| SCHEMBL23879802 | 0.74 | KDM4E (0.50) | KDM4ELMNAMMP1MMP3MMP7 | |
| SCHEMBL3308377 | 0.74 | MMP3 (0.51) | KDM4ELMNAMMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136251-B2 | Compositions, methods, and devices for capturing phosphate from water | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11136251-B2 | Compositions, methods, and devices for capturing phosphate from water | PPA1, ACP3, CASR | KDM4E 2964/4885LMNA 3172/4885MMP1 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.