SCHEMBL2388007

SCHEMBL2388007

CCCCNCCCC([SiH3])(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CA12 O43570 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH7 P40394 1/20 0.32
CA7 P43166 1/20 0.32
CYP2C19 P33261 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
GLA P06280 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57170 0.85 CYP2C19 (0.44) TSHRCYP2C19KMT2AMEN1GLA
SCHEMBL40404 0.83 CA12 (0.44) TSHRALDH1A1CA12CA14CA1
SCHEMBL3655924 0.82 TSHR (0.32) TSHR
SCHEMBL56116 0.81 TSHR (0.42) TSHRALDH1A1ADH1BADH1CADH1A
Ammonia Solution, Strong SCHEMBL22712951 0.80 CA12 (0.41) TSHRALDH1A1CA12CA14CA1
SCHEMBL2385119 0.80 TSHR (0.34) TSHRALDH1A1
SCHEMBL7898954 0.80 PAOX (0.36) CYP2C19KMT2AMEN1
SCHEMBL7911596 0.79 TDP1 (0.47) TSHRALDH1A1CYP2C19KMT2AMEN1
SCHEMBL21463023 0.78 CA12 (0.35) ALDH1A1CA12CA14CA1CA2
SCHEMBL23748415 0.78 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN claimed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US claimed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP claimed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US claimed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP claimed
US-11920038-B2 Method for manufacturing processed cork chip and method for constructing floor using same A-ROAD CO. (KR) 2024-03-05 US disclosed
CN-113966360-A Compositions comprising silylated polymers 亨茨曼国际有限公司 2022-01-21 CN disclosed
US-20210163747-A1 METHOD FOR MANUFACTURING PROCESSED CORK CHIP AND METHOD FOR CONSTRUCTING FLOOR USING SAME A-ROAD CO. (KR) 2021-06-03 US disclosed
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN disclosed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US disclosed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP disclosed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US disclosed
US-20130303804-A1 Process For Preparing A Thixotroping Agent And Use Thereof CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-11-14 US disclosed
US-20120225983-A1 ADHESIVES AND SEALANTS COMPRISING ESTERS BASED ON 2-PROPYLHEPTANOL BASF SE (DE) 2012-09-06 US disclosed
CN-101405316-B Moisture-curing compositions with good adhesion containing silane-functional polymers and aminosilane adducts SIKA TECHNOLOGY AG 2012-03-14 CN disclosed
US-20110232825-A1 CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES AS PLASTICIZERS FOR ADHESIVES AND SEALANTS BASF SE (DE) 2011-09-29 US disclosed
US-8012302-B2 Moisture-curing compositions containing silane-functional polymers and aminosilane adducts with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-09-06 US disclosed
CN-101405316-A Moisture-curing compositions with good adhesion containing silane-functional polymers and aminosilane adducts SIKA TECHNOLOGY AG (CH) 2009-04-08 CN disclosed
US-20090081470-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers and Aminosilane Adducts With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-03-26 US disclosed
US-20070055038-A1 Adducts containing isocyanate groups and composition adhering effectively to painted substrates SIKA TECHNOLOGY AG (CH) 2007-03-08 US disclosed