Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380430 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL380031 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1TSHR | |
| SCHEMBL7898954 | 0.79 | PAOX (0.36) | PAOXCYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL40404 | 0.79 | CA12 (0.44) | TDP1CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL2388007 | 0.79 | TSHR (0.42) | CYP2C19ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9168392 | 0.77 | TDP1 (0.50) | TDP1PAOXCYP2C9CYP2C19KDM4E | |
| SCHEMBL57170 | 0.76 | CYP2C19 (0.44) | CYP2C19MEN1KMT2ATSHR | |
| Ammonia Solution, Strong SCHEMBL22712951 | 0.76 | CA12 (0.41) | TDP1CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL379301 | 0.75 | ALDH1A1 (0.31) | TDP1ALDH1A1TSHR | |
| SCHEMBL15859 | 0.74 | TDP1 (0.75) | TDP1PAOXCYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201058-B1 | POLYMERS WITH REVERSE CHANGES, TEMPERATURE SENSITIVE | WACKER-CHEMIE GMBH (DE) | 2001-03-13 | — | — | US | disclosed |