Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.50 |
| ▸ | TUBB | P07437 | 3/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556162 | 0.85 | KDM4E (0.51) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL9555823 | 0.82 | ALDH1A1 (0.44) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL21127512 | 0.81 | KDM4E (0.56) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL7411788 | 0.81 | KDM4E (0.67) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL23882552 | 0.81 | RAB9A (0.69) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL6929859 | 0.80 | KDM4E (0.65) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL2180069 | 0.80 | RAB9A (0.63) | KDM4ELMNAALDH1A1MAPK1POLB | |
| SCHEMBL23882607 | 0.80 | KDM4E (0.65) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL30186039 | 0.80 | KDM4E (0.65) | KDM4EHSD17B10LMNATUBB4ATUBB | |
| SCHEMBL9386679 | 0.79 | ALDH1A1 (0.44) | KDM4EHSD17B10LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198191-A1 | QUINAZOLINONE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | ENYO PHARMA (FR) | 2021-10-07 | — | — | WO | disclosed |
| WO-2021198191-A1 | QUINAZOLINONE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | ENYO PHARMA (FR) | 2021-10-07 | — | — | WO | disclosed |