Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.60 |
| ▸ | STAT3 | P40763 | 5/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | IL1B | P01584 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451339 | 0.96 | CRBN (0.69) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL19451351 | 0.95 | CRBN (0.66) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL21070288 | 0.95 | CRBN (0.68) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL17873752 | 0.95 | CRBN (0.70) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL21070656 | 0.94 | CRBN (0.67) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL19436953 | 0.94 | CRBN (0.69) | CRBNCA2DDB1HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL21070400 | 0.94 | CRBN (0.67) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL24142128 | 0.94 | CRBN (0.68) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL23884378 | 0.94 | CRBN (0.68) | CRBNCA2DDB1HDAC1HDAC2 | |
| SCHEMBL22280101 | 0.94 | CRBN (0.68) | CRBNCA2DDB1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021201577-A1 | HMG-COA REDUCTASE DEGRADATION INDUCING COMPOUND | UPPTHERA (KR) | 2021-10-07 | — | — | WO | disclosed |