Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043620 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAP2RX7KMT2A | |
| SCHEMBL2044450 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2051564 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2052241 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2052243 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2051576 | 0.78 | MAPT (0.43) | ALDH1A1GAAP2RX7KMT2AGRM4 | |
| SCHEMBL2051578 | 0.78 | MAPT (0.43) | ALDH1A1GAAP2RX7KMT2AGRM4 | |
| SCHEMBL2054268 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2054269 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2053724 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | PADI1, TH, H1-3 | ALDH1A1 1184/4885KDM4E 2907/4885GAA 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.