Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 19/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | MET | P08581 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23888714 | 0.87 | CSF1R (0.43) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL29100364 | 0.86 | CSF1R (0.42) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL23900758 | 0.83 | CSF1R (0.42) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL23888677 | 0.81 | CSF1R (0.39) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL30086888 | 0.81 | CSF1R (0.39) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL25212539 | 0.80 | CSF1R (0.44) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL30086972 | 0.78 | PIM1 (0.51) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL23888703 | 0.78 | PIM1 (0.51) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL23900467 | 0.78 | TGFBR1 (0.47) | CSF1RPDGFRAPDGFRBKDRMET | |
| SCHEMBL2416158 | 0.75 | CSF1R (0.54) | CSF1RPDGFRAPDGFRBKDRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126844-A1 | AMIDE COMPOUNDS AND USES THEREOF | Hutchison Medipharma Limited (CN) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021197276-A1 | Amide compounds and uses thereof | HUTCHISON MEDIPHARMA LIMITED (CN) | 2021-10-07 | — | — | WO | disclosed |