SCHEMBL25212539

SCHEMBL25212539

Nc1ccc(Oc2ccnc(-c3cnn(CCNC(=O)O)c3)c2)cn1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 0.44
▸ PDGFRA P16234 9/20 0.44
▸ PDGFRB P09619 6/20 0.44
▸ MET P08581 3/20 0.44
▸ KDR P35968 3/20 0.44
▸ FLT3 P36888 2/20 0.44
▸ KIT P10721 8/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23900758 0.87 CSF1R (0.42) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL25215305 0.85 CSF1R (0.45) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL29100364 0.83 CSF1R (0.42) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL23888703 0.80 PIM1 (0.51) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL30086972 0.80 PIM1 (0.51) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL23888707 0.80 CSF1R (0.42) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL23900467 0.80 TGFBR1 (0.47) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL25249929 0.79 CSF1R (0.48) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL2416158 0.77 CSF1R (0.54) CSF1RPDGFRAPDGFRBMETKDR
SCHEMBL30086949 0.77 CSF1R (0.54) CSF1RPDGFRAPDGFRBMETKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174513-A1 AMIDE COMPOUNDS AND USES THEREOF HUTCHISON MEDIPHARMA LIMITED (CN) 2023-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174513-A1 AMIDE COMPOUNDS AND USES THEREOF ASNS, ASS1, NAT1 CSF1R 2941/4885PDGFRA 3533/4885PDGFRB 3922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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