2-Pyrrolidone

2-Pyrrolidone

SCHEMBL2389

O=C1CCCN1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL27827832 1.00
2-Pyrrolidone SCHEMBL9304498 1.00 OR51E2 (1.00)
2-Pyrrolidone SCHEMBL4299593 1.00
2-Pyrrolidone SCHEMBL2167448 1.00 OR51E2 (1.00)
2-Pyrrolidone SCHEMBL3453306 0.97
2-Pyrrolidone SCHEMBL5274639 0.97
2-Pyrrolidone SCHEMBL511486 0.97
2-Pyrrolidone SCHEMBL11328078 0.97
2-Pyrrolidone SCHEMBL21858973 0.97
2-Pyrrolidone SCHEMBL9510 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 734962 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9974752-B2 Methods and compositions particularly for treatment of attention deficit disorder PURDUE PHARMA (CA) 2018-05-22 US claimed
US-9976072-B2 Multicarboxylate compositions and method of making the same CHEVRON U.S.A. INC. (US) 2018-05-22 US claimed
WO-2018087361-A1 ORAL PHARMACEUTICAL COMPOSITIONS OF DEXKETOPROFEN AND ELETRIPTAN SANOVEL ILAC SANAYI VE TICARET A.S. (TR) 2018-05-17 WO claimed
US-20180133373-A1 NEUROTROPHIC FACTOR CARRIER, METHOD FOR PRODUCING THE SAME, AND METHOD FOR REGENERATING A NERVE USING THE SAME WIREGENE CO., LTD. (KR) 2018-05-17 US claimed
WO-2018087495-A1 COLLOIDAL SUSPENSION OF FUNCTIONALISED NANOPARTICLES OF A FLUORIDE OF AN ALKALINE-EARTH ELEMENT MATHYM (FR) 2018-05-17 WO claimed
WO-2018089330-A2 SGC STIMULATORS IRONWOOD PHARMACEUTICALS, INC. (US) 2018-05-17 WO claimed
WO-2018089761-A1 DISINFECTANT COMPOSITION HAVING RESIDUAL BIOCIDAL PROPERTIES LONZA INC. (US) 2018-05-17 WO claimed
US-20180133215-A1 SOMCL-9112 SOLID DISPERSION AND PREPARATION METHOD THEREOF AND SOMCL-9112 SOLID PREPARATION CONTAINING SOMCL-9112 SOLID DISPERSION SHANGHAI ACEBRIGHT PHARMACEUTICALS CO., LTD. (CN) 2018-05-17 US claimed
US-20180132481-A1 DISINFECTANT COMPOSITION HAVING RESIDUAL BIOCIDAL PROPERTIES Arxada, LLC 2018-05-17 US claimed
US-20180134695-A1 COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF ABL1, ABL2 AND BCR-ABL1 NOVARTIS AG (CH) 2018-05-17 US claimed
US-3935035-A CHROMIUM COMPOUND NIPPON STEEL CORPORATION (JA) 1976-01-27 US claimed
US-3935334-A Process for preparing a metallized resin film for condenser element OIKE & COMPANY, LTD. (JA) 1976-01-27 US claimed
US-3935326-A Process for coating tablets with aqueous resin dispersions BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-01-27 US claimed
US-3933508-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, BINDER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US claimed
US-3933587-A IRRADIATING A RADIORESISANT ENZYME IN A POLYVINYL POLYMER SOLUTION AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) 1976-01-20 US claimed
US-3933756-A Process of preparation of synthetic resins by reacting a cross-linked isocyanate polyaddition product with low molecular weight polyisocyanate followed by reaction with an amino alkyl silane BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US claimed
US-3933873-A Preparation of omega-aminoalkanoic acids TEXACO INC. (US) 1976-01-20 US claimed
US-3932190-A Plaster of Paris bandages bonded with minimal proportions of hydrolyzed polyvinyl esters SMITH DAVID F 1976-01-13 US claimed
US-3932510-A BY ISOMERIZATION OF DELTA-ENOL LACTONE HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-13 US claimed
US-3931002-A PROCESS FOR REMOVING HEAVY METALS FROM SOLUTIONS STAMICARBON B.V. (NL) 1976-01-06 US claimed