⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL27827832 | 1.00 | — | — | |
| 2-Pyrrolidone SCHEMBL2389 | 1.00 | — | — | |
| 2-Pyrrolidone SCHEMBL9304498 | 1.00 | OR51E2 (1.00) | — | |
| 2-Pyrrolidone SCHEMBL2167448 | 1.00 | OR51E2 (1.00) | — | |
| 2-Pyrrolidone SCHEMBL3453306 | 0.97 | — | — | |
| 2-Pyrrolidone SCHEMBL5274639 | 0.97 | — | — | |
| 2-Pyrrolidone SCHEMBL511486 | 0.97 | — | — | |
| 2-Pyrrolidone SCHEMBL11328078 | 0.97 | — | — | |
| 2-Pyrrolidone SCHEMBL21858973 | 0.97 | — | — | |
| 2-Pyrrolidone SCHEMBL9510 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324580-A1 | Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases | CENIX BIOSCIENCE GMBH (DE) | 2009-12-31 | — | — | US | claimed |
| US-8507546-B2 | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2013-08-13 | — | — | US | disclosed |
| US-20120276121-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2012-11-01 | — | — | US | disclosed |
| US-20090324580-A1 | Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases | CENIX BIOSCIENCE GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-1991215-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | Cenix Bioscience GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |
| US-20080200527-A1 | Cannabinoid Receptor Modulators | CAREX SA (FR) | 2008-08-21 | — | — | US | disclosed |
| EP-1928859-A1 | PYRAZOLE DERIVATES AS CANNABINOID RECEPTOR MODULATORS | Carex SA (FR) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007101710-A1 | USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES | CENIX BIOSCIENCE GMBH (DE) | 2007-09-13 | — | — | WO | disclosed |
| WO-2006133926-A1 | PYRAZOLE DERIVATES AS CANNABINOID RECEPTOR MODULATORS | CAREX SA (FR) | 2006-12-21 | — | — | WO | disclosed |
| US-RE29003-E | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3957758-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3956323-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-11 | — | — | US | disclosed |