2-Pyrrolidone

2-Pyrrolidone

SCHEMBL9304498

O=C1CCCN1.O=C1CCCN1.O=C1CCCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 1.00
CRBN Q96SW2 5/20 0.82
FKBP5 Q13451 1/20 0.82
GAA P10253 3/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 1/20 0.46
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.32
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32
GRIA4 P48058 1/20 0.32
HSP90AA1 P07900 1/20 0.32
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL27827832 1.00
2-Pyrrolidone SCHEMBL2389 1.00
2-Pyrrolidone SCHEMBL4299593 1.00
2-Pyrrolidone SCHEMBL2167448 1.00 OR51E2 (1.00) OR51E2CRBNFKBP5GAAKDM4E
2-Pyrrolidone SCHEMBL3453306 0.97
2-Pyrrolidone SCHEMBL5274639 0.97
2-Pyrrolidone SCHEMBL511486 0.97
2-Pyrrolidone SCHEMBL11328078 0.97
2-Pyrrolidone SCHEMBL21858973 0.97
2-Pyrrolidone SCHEMBL9510 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5376169-A Nonaqueous solvent, pigment, resin and at least one additive from alginates and borneols MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1994-12-27 US disclosed
US-5093031-A Surface active lactams ISP INVESTMENTS INC. (US) 1992-03-03 US disclosed