Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872556 | 0.79 | CHRNB2 (0.37) | CHRNB2CHRNA4MEN1KMT2ACHRM2 | |
| SCHEMBL14707175 | 0.78 | MEN1 (0.42) | CHRNB2CHRNA4MEN1KMT2ACHRM2 | |
| SCHEMBL3478490 | 0.76 | — | — | |
| SCHEMBL18699689 | 0.75 | MEN1 (0.34) | CHRNB2CHRNA4MEN1KMT2ACHRM2 | |
| SCHEMBL15359184 | 0.75 | MGAM (0.41) | CHRNB2CHRNA4MEN1KMT2ACHRM2 | |
| SCHEMBL8064652 | 0.72 | ALDH1A1 (0.41) | LMNA | |
| SCHEMBL29879121 | 0.72 | BLM (0.36) | CHRNB2CHRNA4MEN1KMT2ACHRM2 | |
| SCHEMBL10244731 | 0.72 | — | — | |
| SCHEMBL464490 | 0.72 | CHRNB2 (0.43) | CHRNB2CHRNA4MEN1KMT2ACHRM2 | |
| SCHEMBL16526222 | 0.71 | KDM5A (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889154-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |