Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20623154 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL21203621 | 0.85 | TNF (0.49) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL20427371 | 0.80 | MEN1 (0.60) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL598398 | 0.80 | HSD17B1 (0.59) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL20623157 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL20623158 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL4331306 | 0.79 | TNF (0.53) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL30645491 | 0.79 | TNF (0.53) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL20623106 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1HPGDMAPTCA12 | |
| SCHEMBL12952471 | 0.78 | MCL1 (0.46) | KDM4EALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3518303-B1 | N-(4-(8-(PHENYL)NAPHTHALEN-2-YL)PHENYL)-N,N'-DI(PHENYL)-AMINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC ELECTROLUMINESCENCE DEVICES | SAMSUNG DISPLAY CO LTD (KR) | 2021-10-06 | — | — | EP | disclosed |