Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17605847 | 0.73 | EP300 (0.43) | NR1H2 | |
| SCHEMBL22040127 | 0.73 | EP300 (0.43) | NR1H2 | |
| SCHEMBL17605850 | 0.73 | EP300 (0.43) | NR1H2 | |
| SCHEMBL22040804 | 0.69 | NR1H2 (0.34) | NR1H2PLA2G10PLA2G5 | |
| SCHEMBL30695755 | 0.68 | NR1H2 (0.45) | NR1H2 | |
| SCHEMBL23891532 | 0.66 | EP300 (0.42) | — | |
| SCHEMBL23891705 | 0.65 | EP300 (0.42) | — | |
| SCHEMBL30695726 | 0.65 | NR1H2 (0.61) | NR1H2 | |
| SCHEMBL30468491 | 0.65 | NR1H2 (0.68) | NR1H2 | |
| SCHEMBL22040148 | 0.65 | NR1H2 (0.35) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |