Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FSHR | P23945 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23878337 | 0.91 | CA1 (0.37) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL22039489 | 0.91 | CA1 (0.37) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL23891780 | 0.88 | CTSK (0.35) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL23878305 | 0.80 | KMT2A (0.37) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL22039736 | 0.80 | KMT2A (0.37) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL25321256 | 0.76 | CTSK (0.42) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL25321261 | 0.76 | CTSK (0.42) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL30953384 | 0.76 | AAK1 (0.39) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL31094703 | 0.76 | AAK1 (0.39) | CTSKCTSSKMT2ACA1CA2 | |
| SCHEMBL28027174 | 0.76 | P2RX7 (0.44) | CTSKCTSSHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |